ArcA

Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. Controls the resistance of E.coli to dyes; required for expression of the alkaline phosphatase and sex factor F genes; It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter. Mw; 27,000

Image

In vitro autophosphorylation of ArcA in the presence of acetyl phosphate. Typical images of time-course autophosphorylation.

 

Related data

E.coli ArcB/ArcA, in vitro kinase assay